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为探讨慢性阻塞性肺疾病(COPD)患者静态肺功能指标与运动耐力和通气反应的关系,对29例COPD患者进行了静态肺功能及踏车递增运动肺功能测定。结果:VO2max/VO2maxp(最大耗氧量/最大耗氧量预计值)与FEV1/FVC(1秒钟用力呼气量/最大肺活量)、MVV/MVVp(最大通气量/最大通气量预计值)呈正相关,且与后者相关性最好。IC(深吸气量)与VTmax(最大运动时潮气量)有明显相关性,IC越大则VTmax越大,Fmax(最大运动时呼吸频率)越小;运动的初始阶段,患者与正常人通气反应相同,随运动的继续VE(最大运动时每分钟通气量)达20L/min时,Raw(气道阻力)大、FEV1/FVC小者先出现频率加快,而潮气量增加相应较慢,当运动持续至VE≥30L/min时,Raw小、FEV1/FVC大者也出现了以上通气反应的变化。提示:COPD患者根据其静态肺功能指标可预测患者的运动耐力和运动时的通气反应。
To investigate the relationship between static pulmonary function parameters and exercise tolerance and ventilatory response in patients with chronic obstructive pulmonary disease (COPD), 29 patients with COPD underwent static lung function test and treadmill exercise test. Results: VO2max / VO2maxp (expected value of maximal oxygen consumption / maximal oxygen consumption) was positive with FEV1 / FVC (forced expiratory volume per 1 second) and MVV / MVVp (maximal ventilation / maximal ventilation predicted value) Related, and the latter is the best correlation. There was a significant correlation between IC (deep inspiratory volume) and VTmax (tidal volume at maximum exercise). The larger the IC, the larger the VTmax and the smaller the Fmax (respiratory rate at maximum exercise). The initial stage of exercise, the patient and the normal The same reaction, with the movement of VE (maximum exercise ventilation per minute) up to 20L / min, Raw (airway resistance), FEV1 / FVC small first appear faster, and the corresponding increase in tidal volume slower, when Movement continued to VE ≥ 30L / min, Raw small, FEV1 / FVC greater also appeared above the change of ventilation response. Tip: Patients with COPD can predict exercise endurance and ventilatory response during exercise based on their static lung function.