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目的了解安徽省先天性甲状腺功能减低症(congenital hypothyroidism,CH)发病率与季节、温度之间的关系,为降低CH发病率提供科学依据。方法通过对2001-2012年CH发病情况回顾性研究,采用Spearman相关分析来探讨发病率与环境温度之间的关系。结果在690例CH中,有34.78%分布在暖季,65.22%分布在冷季,冷季发病率高于暖季,差异有统计学意义(P<0.05)。月发病率与环境温度之间有一定相关性,男性患儿的相关性高于女性患儿。结论安徽省CH发病率存在与季节及温度相关性特征。
Objective To understand the relationship between the incidence of congenital hypothyroidism (CH) and the seasons and temperature in Anhui Province, and to provide a scientific basis for reducing the incidence of CH. Methods By retrospective study on the incidence of CH in 2001-2012, Spearman correlation analysis was used to explore the relationship between incidence and ambient temperature. Results Among 690 CHs, 34.78% were in the warm season, 65.22% were in the cold season, and the incidence in the cold season was higher than that in the warm season. The difference was statistically significant (P <0.05). There is a certain correlation between monthly incidence and ambient temperature, and the correlation between male children and female children is higher. Conclusion The incidence of CH in Anhui Province is related to the seasonal and temperature characteristics.