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目的 :探讨巨细胞病毒 (CMV)感染在肾移植术后的发生率及CMV感染与排斥反应的关系。方法 :检测2 0 8例肾移植受者术后CMVDNA和 48例肾移植受者血清CMVIgM、IgG抗体。并定期复查CMVDNA ,对CMVDNA阳性的患者给予抗病毒治疗。结果 :术后CMVDNA阳性受者急性排斥反应的发生率增加 ,经抗CMV治疗 ,则排斥反应减少。结论 :预防和治疗CMV感染的重要性
Objective: To investigate the incidence of cytomegalovirus (CMV) infection after renal transplantation and the relationship between CMV infection and rejection. Methods: Serum CMV IgG and IgG antibodies were detected in 280 patients with renal transplant recipients after CMVDNA and 48 renal transplant recipients. CMVDNA was regularly reviewed and anti-viral therapy was given to CMVDNA-positive patients. Results: The incidence of acute rejection in CMVDNA positive recipients was increased after operation. The anti-CMV treatment reduced the rejection. Conclusion: The importance of preventing and treating CMV infection