Kikuchi病(Kikuchi’s disease,KD)是一种以颈部淋巴结肿大和发热为特征的自限性坏死性淋巴结炎。虽然有文献报道该病可累及皮肤,但相关皮肤损害特征尚未被充分认识,因此作者回顾了16例经淋巴结及皮肤活检证实且伴有皮肤累及的KD患者,并进行了免疫组化、免疫荧光与EBER原位杂交检测。 Kikuchi’s disease (KD) is a self-limiting necrotizing lymphadenitis characterized by swollen lymph nodes and fever. Although it has been reported in the literature that the skin can be affected by the disease, the features of the related skin lesions have not yet been fully understood. Therefore, the authors reviewed 16 KD patients with skin-involvement and lymph node and skin biopsy confirmed by immunohistochemistry, immunofluorescence In situ hybridization with EBER detection.