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目的:探讨噻托溴铵治疗尘肺并发慢性阻塞性肺疾病(COPD)的临床效果。方法:以2014年1月-2015年1月本院收治的120例尘肺并发COPD患者为研究对象,将其随机分为观察组和对照组,给予对照组常规治疗,观察组则在常规治疗的基础上辅以噻托溴铵干粉剂吸入治疗,对比分析两组患者临床疗效及肺功能变化情况。结果:治疗后,观察组治疗总有效率为93.3%,对照组治疗总有效率为71.7%,两组对比,观察组明显高于对照组,P<0.05,差异具有统计学意义;观察组肺功能改善情况明显优于对照组,P<0.05,差异具有统计学意义。结论:噻托溴铵治疗尘肺并发慢性阻塞性肺疾病有较好临床效果,能改善患者肺功能,提升临床治疗效果,值得深入研究和推广。
Objective: To investigate the clinical effect of tiotropium in the treatment of pneumoconiosis complicated with chronic obstructive pulmonary disease (COPD). Methods: From January 2014 to January 2015, 120 patients with pneumoconiosis and COPD admitted to our hospital were enrolled in this study. They were randomly divided into observation group and control group. The patients in control group were given routine treatment and those in observation group were treated with conventional therapy On the basis of intravenous tiotropium powder inhalation therapy, comparative analysis of two groups of patients with clinical efficacy and changes in lung function. Results: After treatment, the total effective rate was 93.3% in the observation group and 71.7% in the control group. The observation group was significantly higher than that of the control group (P <0.05), and the difference was statistically significant. In the observation group, Function improvement was significantly better than the control group, P <0.05, the difference was statistically significant. Conclusion: Tiotropium treatment of pneumoconiosis complicated with chronic obstructive pulmonary disease has good clinical effect, can improve lung function and improve the clinical effect, it is worth further study and promotion.