论文部分内容阅读
目的探讨原发性高血压患者的动脉硬化指数(AASI)与患者并发心律失常的的相关性。方法选择我院老年医学中心收治的230例确诊原发性高血压患者同时进行24h动态心电图及24h动态血压监测,分为AASI≥50%组(中位数)和AASI<50%组(中位数),通过统计两组患者24h动态心电图监测中发生心律失常的情况并进行组间比较。结果 AASI≥50%组患者的高血压病程(14.6±4.8)年、24h收缩压(158.2±11.6)mm Hg、24h舒张压(73.9±8.2)mm Hg均显著的高于AASI<50%组患者且差异均具有统计学意义(p<0.05);两组患者的BMI、TC、TG、HDL-C、LDL-C、吸烟率比较差异不具有统计学意义(p>0.05)。AASI≥50%组患者的SDNN(80.3±18.2)ms、SDNNI(42.6±5.2)ms、PNN50(7.3±4.1)%、SDANN(82.5±14.9)ms、RMSDD(19.8±8.1)ms低于AASI<50%组患者且差异均具有统计学意义(p<0.05)。AASI≥50%组患者的室性期前收缩、复杂性室性心律失常、房性期前收缩、复杂性房性心律失常、左室高电压发生率均显著高于AASI<50%组患者且差异均具有统计学意义(p<0.05)。结论原发性高血压患者的动脉硬化指数≥50%中位数患者的心律失常发生率显著增高,所以对于这一部分患者严控患者血压、改善心肌重构对于预防高血压所致心律失常具有重要意义。
Objective To investigate the correlation between arteriosclerosis index (AASI) and arrhythmia in patients with essential hypertension. Methods 230 patients diagnosed as essential hypertension admitted to the Geriatric Center of our hospital were examined by 24-hour ambulatory electrocardiogram (ECG) and 24-hour ambulatory blood pressure monitoring at the same time. The patients were divided into AASI≥50% group (median) and AASI <50% Number), through the statistics of two groups of patients 24h ambulatory ECG monitoring arrhythmia occurred and compared between groups. Results The duration of hypertension (158.2 ± 11.6) mm Hg at 24h and diastolic blood pressure at 24h (73.9 ± 8.2) mm Hg in patients with AASI≥50% were significantly higher than those with AASI <50% at 14.6 ± 4.8 years The difference was statistically significant (p <0.05). The BMI, TC, TG, HDL-C, LDL-C and smoking rates of two groups had no significant difference (p> 0.05). SDNN (42.6 ± 5.2) ms, PNN50 (7.3 ± 4.1)%, SDANN (82.5 ± 14.9) ms and RMSDD (19.8 ± 8.1) ms in patients with AASI≥50% were lower than those in patients with AASI < 50% of the patients and the differences were statistically significant (p <0.05). Premature ventricular contractions, complex ventricular arrhythmia, atrial premature atrial contraction, complex atrial arrhythmias, and left ventricular high voltage were significantly higher in patients with AASI≥50% than those with AASI <50% The differences were statistically significant (p <0.05). Conclusions The incidence of arrhythmia in patients with essential hypertension with ≥50% median arteriosclerosis index is significantly higher, so it is important for this part of patients to control blood pressure and improve myocardial remodeling to prevent arrhythmia caused by hypertension significance.