德国研究人员近日报告说,他们发现皮肤样本分析或有助于帕金森病早期诊断与研究。α-突触核蛋白是常见于人脑的一种蛋白质,多存在于神经元(神经细胞)末端的突触前末梢内。突触前末梢能释放统称为神经递质的化学物质,神经递质负责在神经元间传递信号,对维持正常脑功能起到关键作用。先前研究发现,α-突触核蛋白聚集成块会导致释放神经递质“多巴胺”的神经元死亡,而多巴胺的减少会引发帕金森病。 German researchers recently reported that they found that skin sample analysis or contribute to the early diagnosis and research of Parkinson’s disease. Alpha-synuclein is a protein found in the human brain that is found mostly in the presynaptic terminals distal to neurons (nerve cells). The presynaptic terminals release chemicals, collectively known as neurotransmitters, which are responsible for signaling between neurons and play a key role in maintaining normal brain function. Previous studies have found that the aggregation of α-synuclein into blocks can result in the death of neurons that release the neurotransmitter “dopamine,” while the reduction in dopamine triggers Parkinson’s disease.