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目的：探讨CT能谱成像在鉴别门静脉良恶性栓子中的诊断价值。方法回顾性分析58例肝癌并门静脉栓子的CT能谱图像，利用GSI后处理软件检测肝内原发灶及门静脉栓子40～140 Kev不同单能量下的CT值，依据所得数据分为门静脉癌栓组（n＝32）和门静脉血栓组（n＝26），分别比较两组肝内原发灶与门静脉栓子在不同Kev下CT的值。结果门静脉癌栓组肝内原发灶与门静脉栓子不同单能量下CT值的差异无统计学意义（ P＞0．05），门静脉血栓组差异有统计学意义（P＜0．05）。结论 CT能谱成像是一种新的无创性检查方法，可为临床门静脉栓子类型的确诊提供依据。“,”Objective To investigate the application value of spectral CT in the differential diagnosis of benign and ma-lignant portal vein thrombosis.Methods The spectral CT images of 58 cases of hepatic carcinoma complicated with portal venous emboli were retrospectively analyzed.Single energy CT value (40~140 Kev) of primary hepatic tumors and portal venous emboli were calculated.The datasets were divided into portal tumor thrombus group ( n=32 ) and portal vein thrombosis group ( n=26) and then compared.Results Single energy CT value in the primary hepatic car-cinoma and portal tumor thrombus group was similar (P>0.05), but there was significant difference between primary hepatic carcinoma and portal vein thrombosis (P<0.05).Conclusion The spectral CT as a new and non-invasive method can improve the diagnostic efficiency of portal venous emboli.