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目的:本研究试图通过对部分更年期女性骨代谢物含量的检测,探讨抗阻锻炼对更年期女性骨代谢的影响。方法:试验对象为华南师范大学20名健康绝经女教师,随机分为对照组(对照A组)、抗阻运动组(实验B组),进行为期9个月的实验。在运动干预前、3个月、9个月测定受试者正位腰椎骨密度,并抽取肘前静脉血,测定血清酸性磷酸酶、血清碱性磷酸酶、血钙、血磷等骨代谢指标。结果:1.对照组受试骨量丢失,骨密度下降(P>0.05),抗阻运动组骨密度均增加(P<0.05)。2.实验前、3个月及9个月抗阻运动组的抗酒石酸盐酸性磷酸酶、血清酸性磷酸酶均有下降的趋势。实验前后,抗阻运动组自身对照显示差异具有显著性(P<0.05)。3.对照组血清碱性磷酸酶的活性在实验前、3个月及9个月均无明显变化(P>0.05),抗阻运动组实验前、3个月及9个月血清特异性碱性磷酸酶活性上升明显,具有显著性差异(P<0.05)。4.对照组和抗阻运动组的尿钙与肌酐的比值均呈现下降的趋势(P<0.05),抗阻运动组在9个月后与对照组相比差异具有显著性(P<0.05),抗阻运动组在实验前后自身对比具有显著性差异(P<0.05)。结论:抗阻运动对更年期女性骨密度及骨代谢具有良好的影响,可使骨密度显著增加(P<0.05),血钙、碱性磷酸盐显著降低(P<0.05)。
Objective: In this study, we attempted to explore the effect of anti-resistance exercise on the bone metabolism in climacteric women through examining the bone metabolites of some menopausal women. Methods: Twenty healthy menopausal female teachers in South China Normal University were randomly divided into control group (control group A) and resistance exercise group (experimental group B) for 9 months. The BMD of lumbar vertebra was measured before exercise, 3 months and 9 months, and blood samples of elbow before extraction were collected. Serum acid phosphatase, serum alkaline phosphatase, serum calcium, phosphorus and other indicators of bone metabolism . The bone mineral density and bone mineral density of the control group decreased (P> 0.05), and the BMD of the resistance exercise group increased (P <0.05). Before the experiment, anti-tartrate acid phosphate phosphatase and serum acid phosphatase in resistance exercise group decreased at 3 and 9 months. Before and after the experiment, resistance exercise group self-control showed significant difference (P <0.05). Serum alkaline phosphatase activity in the control group had no significant changes at 3 months and 9 months (P> 0.05), before exercise, 3 months and 9 months in the resistance exercise group Phosphatase activity increased significantly, with significant differences (P <0.05). The ratio of urinary calcium to creatinine in control group and resistance exercise group showed a decreasing trend (P <0.05), and the resistance exercise group had significant difference compared with control group after 9 months (P <0.05) There was significant difference between the resistance exercise group before and after the experiment (P <0.05). CONCLUSION: Anti-resistance exercise has a good effect on bone mineral density and bone metabolism in menopausal women. It can significantly increase the bone mineral density (P <0.05) and decrease the serum calcium and alkaline phosphates (P <0.05).