目的比较阿奇霉素治疗小儿支原体肺炎及红霉素治疗小儿支原体肺炎的疗效观察。方法2002年1月至2007年1月收治的80例支原体肺炎患儿,随机分为观察组40例及对照组40例,观察组用阿奇霉素治疗,对照组用红霉素治疗,其余按肺炎常规治疗,比较观察组与对照组临床疗效、临床症状体征消失时间及不良反应,进行统计学分析。结果观察组与对照组临床疗效比较明显优于对照组,P<0.05;观察组与对照组临床症状体征消失时间比较明显少于观察组,P<0.05,其不良反应发生观察组明显减少。结论用阿奇霉素治疗小儿支原体肺炎明显优于用红霉素治疗小儿支原体肺炎。 Objective To compare the efficacy of azithromycin in the treatment of children with mycoplasma pneumonia and erythromycin in children with mycoplasma pneumonia. Methods 80 cases of mycoplasma pneumonia admitted in our hospital from January 2002 to January 2007 were randomly divided into observation group (40 cases) and control group (40 cases). The observation group was treated with azithromycin and the control group was treated with erythromycin The clinical curative effect, the disappearance time of clinical symptoms and signs and adverse reactions were compared between the observation group and the control group for statistical analysis. Results The clinical curative effect of the observation group and the control group was significantly better than that of the control group (P <0.05). The disappearance time of clinical symptoms and signs in the observation group and the control group was significantly less than that in the observation group (P <0.05), and the adverse reaction was observed in the observation group. Conclusion Azithromycin treatment of children with mycoplasma pneumonia is significantly better than the use of erythromycin in children with mycoplasma pneumonia.