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一例35岁法国女性,曾于1980年9月5日至25日在印度尼西亚旅游,正规地服用氯喹作预防。回法国后还连服2月。患者于10月3日,即还在服氯喹期间,突然发烧10天,但未能证明由于疟疾。10月底及11月中又发作两次,都自行消退。11月30日高烧达40℃入院。薄血片查到许多恶性疟原虫滋养体,间接免疫荧光试验对恶性疟原虫及间日疟原虫抗原都呈阳性。已经证明这是对氯喹有抗性的恶性疟,所以肌肉注射2安瓿的Fa-nsidar(周效磺胺加乙胺嘧啶)。体温迅速下降,血内寄生虫从第2天即消失。2周后病人复检,一切正常。但1981年1月27日疟疾
A 35-year-old French woman who travels in Indonesia from September 5 to September 25, 1980, regularly takes chloroquine for prevention. Back to France after even serving in February. Patients on October 3, that is, while still taking chloroquine, had a sudden fever for 10 days but failed to prove that due to malaria. In late October and mid-November, two episodes of self-escalation took place. November 30 high fever 40 ℃ admission. Thin blood film found many P. falciparum trophozoites, indirect immunofluorescence test for Plasmodium falciparum and Plasmodium vivax antigen were positive. It has been shown that this is Plasmodium falciparum resistant to chloroquine, so intramuscular injection of 2 ampoules of Fa-nsidar (pesium sulphate plus pyrimethamine). Temperature dropped rapidly, blood parasite disappeared from the first 2 days. 2 weeks after the patient review, everything is normal. But January 27, 1981 Malaria