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目的:评价替勃龙片与甲硝唑栓联用对萎缩性阴道炎患者的临床疗效。方法:选取2014年1月—2016年12月期间收治的萎缩性阴道炎患者122例临床资料,采用收治顺序号将其随机分为观察组和对照组,每组61例;对照组患者给予甲硝唑栓外用治疗,观察组患者在对照组治疗基础上加用替勃龙片治疗,比较两组患者治疗前后的阴道p H值的变化情况以及治疗后白带清洁度的改善情况和治疗后的总有效率的差异。结果:治疗前两组患者的阴道p H测得值经组比较其差异无统计学意义(P>0.05),治疗后观察组患者的阴道p H测得值低于对照组(P<0.05);观察组患者白带清洁度Ⅰ、Ⅱ度的比例均高于对照组(P<0.05),白带清洁度Ⅲ、Ⅳ度的比例均低于对照组(P<0.05),治疗后的总有效率高于对照组(P<0.05)。结论:采用替勃龙片与甲硝唑栓联用治疗萎缩性阴道炎患者的临床疗效优于单用甲硝唑栓的疗效,能显著改善患者阴道p H值及白带清洁度。
Objective: To evaluate the clinical efficacy of tibolone tablets and metronidazole suppository in patients with atrophic vaginitis. Methods: A total of 122 patients with atrophic vaginitis were enrolled from January 2014 to December 2016. The patients were randomly divided into observation group and control group, with 61 cases in each group. The patients in control group were given A The external application of nitazoxan, observation group patients in the control group based on the addition of tibolone tablets treatment, compared before and after treatment in patients with vaginal p H value changes and the improvement of post-treatment vaginal cleanliness and post-treatment The total efficiency of the difference. Results: The vaginal p H values of the two groups before treatment were no significant difference (P> 0.05), but the vaginal p H value of the observation group was lower than that of the control group after treatment (P <0.05) (P <0.05). The percentage of grade Ⅲ and grade Ⅳ of vaginal discharge in the observation group was lower than that in the control group (P0.05). The total effective rate Higher than the control group (P <0.05). Conclusion: The clinical efficacy of tibolone tablet and metronidazole suppository in treating atrophic vaginitis is better than that of metronidazole suppository, which can significantly improve the vaginal p H value and vaginal discharge cleanliness.