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目的探讨乳腺导管内视镜检出的0期乳癌施行保乳手术的中期效果。方法把乳腺导管内视镜检出的48例导管内癌患者随机分为两组分别行保乳手术和仿Ⅱ根治术(MRMⅡ),分析治疗效果。结果随访7年到11年7个月(中位8年),两组均无复发及转移。两组均无死亡病例。保乳手术组患者术后在乳房外观和生存质量方面明显优于MRMⅡ组。结论对乳腺导管内视镜检出的0期乳癌施行保留乳房手术是安全可行的。
Objective To investigate the medium-term effect of breast-conserving surgery on stage 0 breast cancer detected by ductal endoscopy. Methods Forty-eight patients with intraductal carcinoma detected by endoscopic ductoscopy were randomly divided into two groups: breast conserving surgery and imitation Ⅱ radical mastectomy (MRMⅡ), respectively. The therapeutic effect was analyzed. The results were followed up for 7 years to 11 years and 7 months (median 8 years), no recurrence and metastasis in both groups. No deaths were reported in both groups. Breast-conserving surgery patients in postoperative breast appearance and quality of life was significantly better than the MRM Ⅱ group. Conclusion It is safe and feasible to perform breast-conserving surgery on stage 0 breast cancer detected by ductal endoscopy.