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目的:总结孟鲁司特治疗过敏性紫癜(henoch-schonlein purpura,HSP)的meta分析,进一步探讨孟鲁斯特在HSP治疗中的临床应用价值。方法:采用计算机检索方式对文献资料进行收集与筛选,对纳入文献进行质量评价,并采用RevMan5.0软件对纳入文献进行Meta分析。结果:纳入文献为8篇,临床治疗有效率方面看,孟鲁司特治疗HSP的疗效较为显著,与对照组比较的RR、95%CI分别为1.46、(1.25~1.61),差异较大(p<0.05),具有统计学意义。结论:应用孟鲁司特治疗HSP的临床效果显著,能够有效改善治疗效果,值得临床推广应用。
OBJECTIVE: To summarize the meta-analysis of montelukast in the treatment of henoch-schonlein purpura (HSP), and to further explore the clinical value of Montelukast in the treatment of HSP. Methods: The documents were collected and screened by computer retrieval method, the quality of the included documents was evaluated, and the included documents were analyzed by Meta-analysis using RevMan 5.0 software. Results: Eight articles were included in the literature, and the efficacy of montelukast in the treatment of HSP was significant compared with the control group (95% CI, 95% CI, 1.46, 1.25-1.61, respectively) p <0.05), with statistical significance. Conclusion: The clinical effect of using montelukast in the treatment of HSP is significant, which can effectively improve the therapeutic effect and is worthy of clinical application.