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目的 提高对原发性中枢神经系统恶性淋巴瘤 (PCNSL)临床特征的认识。方法 回顾性分析经病理证实的 39例PC NSL。结果 该肿瘤多发生于中老年患者 ,男性多见 ;好发于幕上 ,临床上无特征性表现。是否行手术治疗与PCNSL病人的预后无显著相关性 (P >0 0 5)。结论 原发性中枢神经系统恶性淋巴瘤术前易误诊 ,预后不良。手术的主要目的是解除肿瘤引起的颅内高压 ,减轻或解除脑神经功能的进一步废损 ,明确诊断。强调术后常规放疗和化疗 ,是延长生存期并改善生存质量的关键
Objective To raise awareness of the clinical features of primary central nervous system malignant lymphoma (PCNSL). Methods Retrospective analysis of pathologically confirmed 39 cases of PC NSL. Results The tumor occurred in middle-aged and elderly patients, more common in men; occurs in the curtain, no clinical manifestations. There was no significant correlation between surgical treatment and prognosis of PCNSL patients (P> 0.05). Conclusions The preoperative misdiagnosis of primary CNS malignant lymphoma is premature and the prognosis is poor. The main purpose of surgery is to relieve intracranial hypertension caused by the tumor, reduce or relieve further damage to the function of the brain, a clear diagnosis. Emphasize postoperative conventional radiotherapy and chemotherapy is the key to prolong survival and improve quality of life