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目的:测定50例老年充血性心力衰竭患者的血、尿β2-微球蛋白(β2-MG),并与40例正常老年人作对照。方法:回顾分析两组的临床资料。结果:心力衰竭患者血、尿β2-MG水平明显高于正常老年人(P<0.05),而且随着心力衰竭程度的加重,逐渐升高(P<0.05)。结论:结果提示血、尿β2-微球蛋白水平可作为评价心脏功能损害程度的客观敏感指标。
Objective: To determine the blood and urinary β2-microglobulin (β2-MG) in 50 elderly patients with congestive heart failure and compare them with 40 normal controls. Methods: The clinical data of two groups were retrospectively analyzed. Results: Serum and urinary levels of β2-MG in patients with heart failure were significantly higher than those in normal controls (P <0.05), and increased gradually with the severity of heart failure (P <0.05). Conclusion: The results suggest that blood and urine β2-microglobulin levels can be used as an objective and sensitive index to evaluate the degree of cardiac dysfunction.