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目的对2种遗尿症治疗方法进行临床随机对照研究,比较各种治疗方法的特点以及对原发性夜间遗尿症儿童的疗效。方法以65例确诊为原发性夜间遗尿症的患儿为研究对象,在家长和患儿同意进行6个月的治疗并坚持随访情况下,将其随机分为2组:(1)暗示-叫醒组34例,由家长配合训练患儿排尿能力,自然形成条件反射,建立自我控制的排尿习惯。(2)药物治疗组31例,口服氟丙咪嗪片剂按疗程服用。结果暗示-叫醒组的近期和远期治愈为82.35%、73.52%;药物治疗组的近期和远期治愈率分别为41.94、25.81%。暗示-叫醒治疗组的近期、远期疗效均显著优于药物治疗组,P<0.01其显效慢,疗效巩固;药物治疗组起效快,停药后复发率高。结论暗示-叫醒治疗组和药物氯丙咪嗪治疗对我国儿童均具有疗效;但暗示—叫醒组治疗立足于培养儿童的夜间排尿控制能力,较药物治疗疗效更好,且复发率明显低于药物治疗,值得在国内遗尿症治疗中推广应用。
Objective To carry out clinical randomized controlled trials of two enuresis treatments and to compare the characteristics of various treatments and the efficacy of primary nocturnal enuresis. Methods Sixty-five children with primary nocturnal enuresis were enrolled in this study. When parents and children agreed to be treated for 6 months and were followed up, they were randomly assigned to two groups: (1) Wake group 34 cases, accompanied by the training of children with urinary bladder urinary capacity, the natural formation of conditioned reflex, the establishment of self-control of urination habits. (2) 31 cases of drug treatment group, taking oral fluoromethazine tablets taking medication. The results suggest that - the wake of the group of immediate and long-term cure for 82.35%, 73.52%; drug treatment group, the short-term and long-term cure rates were 41.94,25.81%. Suggest - wake up the treatment group, the short-term, long-term efficacy were significantly better than the drug treatment group, P <0.01 its markedly slow, the effect of consolidation; drug treatment group onset fast, relapse rate after stopping high. Conclusions - Wake treatment group and drug clomipramine treatment in children in our country have a curative effect; but hint - wake group treatment based on pediatric nighttime voiding control, better efficacy than drug treatment, and the recurrence rate was significantly lower In drug treatment, it is worth in the promotion of enuresis treatment in the country.