Dandy-Walker综合征又称Dandy-Walker畸形,即第四脑室正中孔、侧孔发生闭锁为其主要原因,病理学改变以第四脑室和小脑发育畸形为特点,导致第四脑室明显扩张及小脑蚓部前移,小脑蚓部全部或部分缺失。临床表现为颅内压增高表现:患儿兴奋性增强、头痛、呕吐等;脑积水征:头围增大、颅缝裂开、前囟扩大隆起,头颅扩大以前后径长为特点,即后颅凹扩大;小脑症状:走路不稳、共济失调、眼球震颇;其他:运动发 Dandy-Walker syndrome, also known as Dandy-Walker deformity, the fourth ventricle center hole, side hole occlusion is the main reason for the pathological changes to the fourth ventricle and cerebellar dysplasia, resulting in significant expansion of the fourth ventricle and cerebellum Vermis move forward, all or part of cerebellar vermis missing. Clinical manifestations of increased intracranial pressure performance: increased excitability in children, headache, vomiting, etc .; hydrocephalus sign: increased head circumference, suture crack, the anterior fontanel enlargement uplift, Posterior fossa enlargement; cerebellar symptoms: walking unsteady, ataxia, nystagmus; others: exercise