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目的:研究用培哚普利联合银杏达莫注射液治疗肺心病急性加重期的效果,并观察此联合用药方法的毒副作用。方法:对2010年9月～2012年3月期间我院收治的100例肺心病急性发作期患者的临床资料进行回顾性研究。我们将这100例患者随机分为治疗组和对照组,每组各有50例患者。对照组患者单独使用培哚普利进行治疗,治疗组患者在应用培哚普利的基础上,加用银杏达莫注射液进行治疗。两周后,比较两组患者治疗的效果和发生不良反应的几率。结果:治疗组患者治疗的总有效率为88%,对照组患者治疗的总有效率为70%,治疗组患者治疗的总有效率明显高于对照组患者,二者相比差异具有显著性(P<0.05)。两组患者在治疗期间均未出现明显的不良反应,二者相比差异无显著性。结论:用培哚普利联合银杏达莫注射液治疗肺心病急性加重期效果显著,不良反应少,值得在临床上推广使用。
Objective: To study the effect of perindopril combined with Yinxingdamo injection in the treatment of acute exacerbation of pulmonary heart disease, and to observe the toxic and side effects of this combination therapy. Methods: The clinical data of 100 patients with acute episode of pulmonary heart disease admitted to our hospital from September 2010 to March 2012 were retrospectively studied. We randomly assigned the 100 patients to treatment and control groups, each with 50 patients in each group. The patients in the control group were treated with perindopril alone. The patients in the treatment group were treated with perindopril plus ginkgo dipyridamole injection. Two weeks later, the effect of treatment and the incidence of adverse reactions in both groups were compared. Results: The total effective rate was 88% in the treatment group and 70% in the control group. The total effective rate of the treatment group was significantly higher than that of the control group, and the difference was significant P <0.05). No significant adverse reactions occurred in both groups during the treatment period, and there was no significant difference between the two groups. CONCLUSION: The combination of perindopril and ginkgo biloba injection in the treatment of acute exacerbation of pulmonary heart disease has obvious effect and few adverse reactions, which is worth popularizing in clinic.