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目的探讨新生儿黄疸与患儿心肌损伤间的相关性。方法选取于本院诊断为新生儿黄疸的患儿87例,其中生理性黄疸52例为观察组1,病理性黄疸35例为观察组2,并随机抽取同期正常新生儿50例为对照组,测定3组新生儿不同时期心肌酶水平。结果观察组1患儿AST、LDH、CK、CK-MB略高于对照组相应指标间存在差异,但差异不具有统计学意义(P>0.05);观察组2患儿诊断时及黄疸消失时AST、LDH、CK、CK-MB均明显高于对照组相应指标,以上差异在统计学上均有意义(P<0.05);观察组2患者黄疸消失时AST、LDH、CK、CK-MB均明显低于其诊断时各指标,差异具有统计学意义(P<0.05)。结论新生儿黄疸可引起心肌酶升高,当患儿为病理性黄疸时可引起不同程度心肌损伤,应加强患儿心肌保护,预防心肌损伤。
Objective To investigate the correlation between neonatal jaundice and myocardial injury in children. Methods 87 cases diagnosed as neonatal jaundice in our hospital were selected, including 52 cases of physiological jaundice as observation group 1, 35 cases of pathological jaundice as observation group 2 and 50 normal newborns at the same period as control group, Three groups of neonatal myocardial enzyme levels at different stages. Results There was a significant difference in AST, LDH, CK and CK-MB between the observation group 1 and the control group, but the difference was not statistically significant (P> 0.05). When the observation group 2 was diagnosed and the jaundice disappeared AST, LDH, CK, CK-MB were significantly higher than the corresponding indicators of the control group, the above differences were statistically significant (P <0.05); the observation group 2 patients with jaundice disappeared AST, LDH, CK, CK- Significantly lower than the indicators of each diagnosis, the difference was statistically significant (P <0.05). Conclusion neonatal jaundice can cause elevated myocardial enzymes, when children with pathological jaundice can cause different degrees of myocardial injury should be strengthened in children with myocardial protection, prevention of myocardial injury.