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综述了环糊精(包括α-环糊精、β-环糊精和γ-环糊精)衍生物在液相有机合成中的应用,主要包括其作为人工合成酶、超分子光学手性源、亲偶极体和微通道反应器在氧化、水解、还原、光催化异构化、1,3-偶极环加成等反应中的应用.其中环糊精衍生物作为人工合成酶应用最广,该催化剂中起催化作用的为环糊精衍生物的修饰基团.与环糊精母体相比,修饰基团的引入增加了环糊精分子中官能团的种类和数量,拓展了环糊精在液相有机合成中的应用,并提高了催化反应的催化活性和选择性.
The applications of cyclodextrins (including α-cyclodextrin, β-cyclodextrin and γ-cyclodextrin) derivatives in liquid phase organic synthesis are reviewed, including their use as synthetic enzymes, supramolecular optical chiral sources , Dipolar dipoles and microchannel reactors in the oxidation, hydrolysis, reduction, photocatalytic isomerization, 1,3-dipolar cycloaddition reactions, etc. Among them cyclodextrin derivatives as the most widely used as synthetic enzyme Wide, the catalytic catalyst for cyclodextrin derivatives modified group compared with the parent cyclodextrins, the introduction of modified groups increased the type and number of functional groups in the cyclodextrin molecules, expanding the cyclodextrin Application of fine in liquid organic synthesis, and improve the catalytic activity of the catalytic reaction and selectivity.