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目的研究异氟烷对幼龄小鼠生长发育趋势的影响。方法按随机分层方法,将64只幼龄小鼠分为2大组,再按完全随机分组方法,将每大组各分为4小组(n=8),即NS组(生理盐水组)、Iso1组、Iso2组和Iso3组,1～5d用跳台仪和避暗仪分别训练小鼠,并测得各组幼龄小鼠体质量。结果避暗训练和跳台训练中,各组幼龄小鼠生长发育趋势不同。在避暗和跳台训练中,NS组、Iso1组在2～3d间体质量出现了下降或增长缓慢的趋势,而Iso2组和Iso3组都按照原来的趋势递增。结论异氟烷在一定时期内可以影响幼龄小鼠的生长发育趋势。
Objective To study the effect of isoflurane on the growth and development of young mice. Methods According to the random stratification method, 64 young mice were divided into 2 groups, and each group was divided into 4 groups (n = 8), ie NS group (NS group) , Iso1 group, Iso2 group and Iso3 group. The mice were trained respectively with a step-down meter and an anechoic device from 1 to 5 days, and the body weight of each group of young mice was measured. Results avoid dark training and jumping training, young mice in each group growth and development trends are different. In avoidance of dark and platform training, body mass of NS group and Iso1 group showed a tendency of slowing down or increasing slowly from 2 to 3 days, while Iso2 group and Iso3 group increased according to the original trend. Conclusion Isoflurane may affect the growth and development of young mice in a certain period of time.