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Fas死亡结构域相关蛋白(Fas death domain-associated protein,Daxx)是一种高度保守核蛋白,能与Fas死亡结构域结合,激活Jun氨基端激酶通路促细胞凋亡,在某些情况下Daxx也具有抗凋亡作用。Daxx在细胞凋亡中起着最重要的作用,这将为某些疾病的发病机制研究提供一定的理论与实践基础。
Fas death domain-associated protein (Daxx) is a highly conserved nuclear protein that binds to the Fas death domain and activates the Jun N-terminal kinase pathway to promote apoptosis. In some cases, Daxx With anti-apoptotic effect. Daxx plays the most important role in apoptosis, which will provide some theoretical and practical basis for the study of the pathogenesis of some diseases.