人体细胞中约有7000种类型各异的蛋白质,而差不多三分之一位于细胞膜上。其中一些将物质转运进出细胞,还有一些则传送细胞活动的信号。它们自身的作用,以及膜蛋白易侵入的本质表明,这样的蛋白质往往成为药物产生药效的突破口。事实上,目前市场上有一半的药物是通过细胞膜蛋白产生疗效的。尽管如此,膜蛋白研究起来却很困难。将膜蛋白从其原有环境中剥离会使它们脱离相互作用的 There are about 7,000 different types of proteins in human cells, while about one-third are on the cell membrane. Some of these transport substances into and out of cells, while others send signals of cellular activity. Their own role as well as the intrusive nature of membrane proteins suggests that such proteins often become a breakthrough in the efficacy of drugs. In fact, half the drugs on the market today work through cell membrane proteins. In spite of this, membrane proteins are difficult to study. Peeling the membrane proteins from their original environment will disengage them