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由于球粒在造粒中有着优越的性能,开发用工业方法制备大小均一、圆球度好、表面光洁的球粒造粒方法有着巨大的应用前景。医药工业缓释、控释制剂的发展更迫切需要开发大规模制造球粒的方法和设备。本文介绍了用挤出滚圆方法制造球形微丸微粒的方法和设备。最新开发、研制的专利产品──球形微丸造粒机能够以工业规模批量制造球粒微九。球粒造粒容易、效率高。本设备不但可以为医药缓释、控释制剂新品种的开发提供装备,也可为食品、化肥、催化剂、精细化工等工业球粒造粒提供合适的设备。
Due to the superior performance of pellets in pelletization, the development of pelletizing methods with uniform size, sphericity and smooth surface by industrial methods has great application prospect. The sustained release of the pharmaceutical industry, the development of controlled release formulations more urgent need to develop large-scale methods and equipment for the manufacture of pellets. This article describes a method and apparatus for producing spherical pellets by extrusion spheronization. The newly developed and developed patented product - spherical pellet pelletizer can be manufactured on an industrial scale pellet micro-nine. Pelleting granulation easy, high efficiency. This equipment not only can provide equipment for the development of new drugs for sustained release and controlled release preparations, but also for the industrial pelletizing of foodstuffs, chemical fertilizers, catalysts and fine chemicals.