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文献中提到狗胃在切断两侧迷走神经后,其胃酸分泌仅暂时受到抑制。鉴于实验提示胃窦粘膜分泌粘液可能是通过交感神经的传出神经,且Lott等报告在用组织胺灌注狗的急性实验中,引起的胃酸分泌也是通过交感途径,据此作者等试图测定是否存在第二条刺激途径,也就是非迷走介导的泌酸反应。根据作者等以前的实验,对用氯醛糖-乌拉坦麻醉的狗作中枢性迷走神经电刺激和摄人苯氧苄胺,可以同时有胃分泌量和可滴定酸的持久升高。本实验所有狗均采用这种麻醉,手术措施、插管技术及中枢性迷走电刺激与以前报告者相同。每条狗均作两侧迷走神经切断及
The reference to the dog’s stomach in the literature after cutting off both sides of the vagus nerve, the gastric acid secretion only temporarily inhibited. In view of the experimental tips gastric mucosa secretion of mucus may be through the sympathetic afferent nerve, and Lott et al reported in dogs with histamine infusion in acute experiments, caused by gastric acid secretion is also through the sympathetic pathway, according to which the author attempts to determine the existence The second stimulus, that is, non-vagal mediated oxyntic reactions. According to previous experiments by authors and others, central vagal electrical stimulation and ingestion of phenoxybenzamine in chloralose-urethane anesthetized dogs can have both gastric secretion and sustained elevation of titratable acid. All dogs in this experiment were anesthetized, surgical interventions, intubation techniques, and central vagal stimulation were the same as previously reported. Each dog is made on both sides of the vagus nerve and cut off