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目的:探讨美沙拉嗪联合益阳愈溃汤治疗溃疡性结肠炎的疗效。方法:根据治疗方案将119例溃疡性结肠炎患者分为观察组(63例)与对照组(56例),观察组患者在常规治疗基础上联合使用美沙拉嗪、益阳愈溃汤治疗,对照组患者在常规治疗基础上联合使用美沙拉嗪治疗。结果:1治疗前,两组患者溃疡性结肠炎活动指数(UCAI)、C反应蛋白(CRP)、血沉(ESR)相比差异无统计学意义(P>0.05);治疗后,观察组UCAI、CRP、ESR显著低于对照组,差异有统计学意义(P<0.05)。2观察组发热、脓血便、腹痛、腹泻等临床症状消失时间显著低于对照组,差异有统计学意义(P<0.05)。3经疗效评价,观察组指标效果显著优于对照组,差异有统计学意义(P<0.05)。结论:美沙拉嗪联合益阳愈溃汤治疗溃疡性结肠炎的疗效确切且恢复快,值得临床推广应用。
Objective: To investigate the curative effect of mesalamine combined with Yiyang Yucui decoction in the treatment of ulcerative colitis. Methods: A total of 119 patients with ulcerative colitis were divided into the observation group (63 cases) and the control group (56 cases) according to the treatment plan. The patients in the observation group were treated with mesalazine and Yiyang Yucui Decoction on the basis of routine treatment. The patients in the group were treated with mesalazine on the basis of routine treatment. Results: Before treatment, there was no significant difference in UCAI, CRP and ESR between the two groups (P> 0.05). After treatment, the UCAI, CRP, ESR was significantly lower than the control group, the difference was statistically significant (P <0.05). The disappearance time of clinical symptoms such as fever, purulent blood, abdominal pain and diarrhea in the observation group was significantly lower than that in the control group (P <0.05). 3 The curative effect evaluation, the effect of the observation group index was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: Mesalazine combined with Yiyang Yucui Decoction for the treatment of ulcerative colitis is effective and rapid recovery, worthy of clinical application.