控制性促排卵是植入前遗传学诊断(PGD)中的关键步骤之一。不同遗传性疾病可供移植的胚胎比例不同,因此对获卵数的要求有所不同。某些遗传性疾病本身对卵巢反应性可能有一定影响。文章首先介绍遗传性疾病中遗传方式决定的可供移植胚胎比例,然后重点分析PGD中控制性促排卵的特点,包括遗传性疾病可能对卵巢反应性的影响以及PGD中促排卵方案的选择和目前文献报道PGD获卵数的截断值。 Controlled ovulation induction is one of the key steps in preimplantation genetic diagnosis (PGD). Different hereditary diseases can be transplanted in different proportions of embryos, so the requirements on the number of ova retrieved are different. Some genetic diseases themselves may have some influence on ovarian response. The article begins with a description of the proportion of embryos available for transplantation that are inherited from hereditary diseases and then focuses on the characteristics of controlled ovulation in PGD, including the possible effect of genetic diseases on ovarian response and ovulation induction in PGD and the current The literature reports the cut-off value of PGD oocyte number.