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目的 了解四川省凉山州地区静脉吸毒人群丙型肝炎病毒感染情况及其危险因素。方法 以社区为基础调查静脉吸毒人群丙型肝炎病毒感染危险因素 ,通过检测研究对象的丙型肝炎病毒抗体确定是否感染丙型肝炎病毒。结果 静脉吸毒人群丙型肝炎病毒感染率为 71.0 % (2 6 9/379)。在多因素 logistic回归模型分析中 (P<0 .0 5 ) ,共用注射器具次数的 OR值为 2 .0 5 3,其 95 %CI为 1.4 5 8～ 2 .891。在单因素χ2 分析中 (P <0 .0 5 ) ,共用注射器具次数、共用注射器具吸毒年限、近 3个月平均每天静脉吸毒频率等多个因素同丙型肝炎病毒感染有关。结论 需进一步研究阐明静脉吸毒共用注射器具方式对丙型肝炎病毒感染的影响
Objective To understand the prevalence and risk factors of hepatitis C virus infection among intravenous drug users in Liangshan Prefecture, Sichuan Province. Methods Based on community survey, the risk factors of hepatitis C virus infection among intravenous drug users were investigated. Hepatitis C virus was determined by detecting the hepatitis C virus antibody in the study subjects. Results The infection rate of hepatitis C virus in intravenous drug users was 71.0% (269/379). In the multivariate logistic regression model analysis (P <0.05), the odds ratio of common syringes was 2.05 3, with a 95% CI of 1.4 5 8 ~ 2.891. In the single factor χ2 analysis (P <0. 05), sharing the number of syringes, syringes with drugs sharing the same period, the average daily intravenous drug intake nearly three months and many other factors associated with hepatitis C virus infection. Conclusion Further study is needed to clarify the effect of intravenous drug use on the infection of hepatitis C virus