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目的探讨T2DM患者焦虑状态和HbA_1c的关系。方法采用多阶段整群随机抽样方法,应用自行设计的一般情况调查表、焦虑抑郁状态自评量表对患者进行调查,并检测HbA_1c。采用多元逐步回归分析模型探讨焦虑状态和HbA_1c的关联。结果焦虑状态患者HbA在c达标率为17.90%(97/542),无焦虑状态患者达标率为25.65%(108/421),两者比较,比较差异有统计学意义(x~2=8.51,P=0.01)。无焦虑、轻度、中度和重度焦虑患者中,血糖达标的比例分别为25.65%(108/421)、18.96%(80/422)、15.18%(17/112)和0.00%(0/8)。T2DM患者焦虑状态程度越严重,患者血糖达标率越低(x~2_(趋势)=10.27,P<0.01),HbA_1c越高(F=4.24,P<0.01)。多元线性逐步回归分析发现,女性、独居、人均月收入低、病程长和焦虑状态是HbA_1c升高的危险因素。结论 T2DM患者焦虑状态与HbA_1c存在关联。
Objective To investigate the relationship between anxiety and HbA_1c in T2DM patients. Methods A multistage cluster random sampling method was used to investigate patients with HbA_1c by using self-designed general condition questionnaire and anxiety-depression status self-rating scale. Multivariate stepwise regression analysis model was used to explore the association between anxiety and HbA_1c. Results The prevalence of HbA was 17.90% (97/542) in patients with anxiety and 25.65% (108/421) in patients without anxiety. There was significant difference between the two groups (x ~ 2 = 8.51, P = 0.01). Among the patients without anxiety, mild, moderate and severe anxiety, the rates of blood glucose compliance were 25.65% (108/421), 18.96% (80/422), 15.18% (17/112) and 0.00% (0/8 ). The more severe the anxiety state in patients with T2DM, the lower the blood glucose compliance rate (x ~ 2_ (trend) = 10.27, P <0.01) and the higher the HbA_1c level (F = 4.24, P <0.01). Multivariate linear stepwise regression analysis found that women, living alone, low per capita income, long duration and anxiety status are risk factors for HbA_1c increased. Conclusion There is an association between anxiety and HbA_1c in T2DM patients.