目的 探讨化疗预防和治疗鼻咽癌远处转移的疗效。方法 对３７例中晚期鼻咽癌患者，２０例３期、４期和病理为未分化癌病人，采用放疗后辅助化疗。结果 放疗后加化疗组的４年生存率明显优于单纯放疗组。结论 放疗后辅助化疗可作为提高鼻咽癌疗效的重要手段。 Objective To investigate the efficacy of chemotherapy in the prevention and treatment of distant metastasis of nasopharyngeal carcinoma. Methods 37 patients with advanced nasopharyngeal carcinoma, 20 patients with stage 3, 4 and pathologically undifferentiated carcinoma were treated with adjuvant chemotherapy after radiotherapy. Results After radiotherapy plus chemotherapy group 4-year survival rate was significantly better than radiotherapy alone group. Conclusion Adjuvant chemotherapy after radiotherapy can be used as an important means to improve the efficacy of nasopharyngeal carcinoma.