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目的观察盐酸贝那普利片联合参附注射液治疗充血性心力衰竭(CHF)的临床疗效。方法 120例CHF患者被随机分为对照组(40例,常规治疗)、治疗1组(40例,常规治疗基础上加盐酸贝那普利片)、治疗2组(40例,常规治疗基础上加盐酸贝那普利片和参附注射液)。疗程为14d。分别于用药前及给药14d后测定左室射血分数(LVEF)、左室短轴缩短率(FS)及心脏指数(CI)。结果与对照组比较,治疗组LVEF、FS、CI显著改善(P<0.05),治疗2组与治疗1组相比心功能有一定改善。结论贝那普利可改善CHF患者心功能,联合参附注射液治疗CHF疗效显著。
Objective To observe the clinical efficacy of benazepril hydrochloride combined with shenfu injection in the treatment of congestive heart failure (CHF). Methods A total of 120 patients with CHF were randomly divided into control group (40 cases, routine treatment), treatment group 1 (40 cases, routine treatment plus benazepril hydrochloride tablets), treatment group 2 (40 cases, based on routine treatment Plus benazepril hydrochloride tablets and Shen Fu injection). Treatment for 14d. Left ventricular ejection fraction (LVEF), left ventricular fractional shortening (FS) and cardiac index (CI) were measured before administration and after administration for 14 days. Results Compared with the control group, the LVEF, FS and CI in the treatment group were significantly improved (P <0.05). The treatment group 2 had a certain improvement in their cardiac function compared with the treatment 1 group. Conclusion benazepril can improve heart function in patients with CHF, combined with shenfu injection of curative effect of CHF.