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目的:探讨对艾滋病患者进行抗病毒治疗后其CD4+T淋巴细胞计数的变化情况。方法 :对2012年5月~2014年5月期间在我市进行抗病毒治疗的120例艾滋病患者的临床资料进行回顾性研究。对这120例患者均进行抗病毒治疗。在进行治疗前及治疗后的6个月和12个月,对患者的CD4+T淋巴细胞进行检测。然后,观察这些患者在不同时期,其CD4+T淋巴细胞计数的变化情况。结果 :在进行治疗前,有21例患者的CD4>200个/㎜3,有99例患者的CD4≤200个/㎜3。经过治疗,CD4>200个/㎜3的患者CD4+T淋巴细胞计数增长的数量明显高于CD4≤200个/㎜3的患者CD4+T淋巴细胞计数增长的数量,二者相比差异具有显著性(P<0.05)。不同传播途径、不同婚姻状况、不同年龄、不同性别的此病患者之间相比,其CD4+T淋巴细胞计数增长的数量无明显差异(P>0.05)。结论 :对艾滋病患者进行抗病毒治疗,有利于控制其HIV的复制,促进其免疫功能的重建,提高其CD4+T淋巴细胞计数,延缓其病情进展的速度。
Objective: To investigate the change of CD4 + T lymphocyte count in AIDS patients after antiviral therapy. Methods: A retrospective study was conducted on the clinical data of 120 AIDS patients who took antiviral therapy in our city from May 2012 to May 2014. The 120 patients were treated with antiviral therapy. Patient CD4 + T lymphocytes were tested before and at 6 months and 12 months after treatment. Then, observe the changes of CD4 + T lymphocyte count in these patients at different times. Results: Prior to treatment, 21 patients had CD4> 200 cells / mm3 and 99 patients had CD4 <200 cells / mm3. After treatment, the number of CD4 + T lymphocyte counts in patients with CD4> 200 cells / mm3 was significantly higher than that in patients with CD4 <200 cells / mm3. There was a significant difference between the two in CD4 + T lymphocyte count (P <0.05). There was no significant difference in the number of CD4 + T lymphocyte counts between patients with different transmission routes, different marital status, different ages and different genders (P> 0.05). Conclusion: Antiviral treatment of AIDS patients is conducive to controlling their HIV replication, promote the reconstruction of immune function, increase their CD4 + T lymphocyte count and delay the progression of their disease.