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目的:研究Mdr基因与肾细胞癌(Rcc)的关系.方法:采用免疫组织化学法检测了正常肾组织和35例Rcc组织切片.结果:Mdr表达与组织学类型相关,且表达量与肿瘤分级有关.结论:Mdr基因在Rcc发生中起重要作用.
Objective: To study the relationship between Mdr gene and renal cell carcinoma (RCC) .Methods: Immunohistochemical method was used to detect normal renal tissue and 35 cases of Rcc tissue sections.Results: Mdr expression was correlated with histological type, and the expression level was correlated with tumor grade .Conclusion: Mdr gene plays an important role in the development of RCC.