the ancient people love building pillow Hill building, along the waterfront, the mountain building not only carry forward Chinese traditional landscape culture, but also make full use of the natural environment of mountains. 2/3 of the land area of China is mountainous, especially in Sicilian, Yunnan, Chongqing, Guangzhou and other southwest of many buildings built in the mountains. Therefore, the mountain building is the only way to realize the sustainable development of the city. The earthquake in the life brought great damage, so far we still have not found a precise method to predict earthquakes, but to take some measures to reduce the harm to the people of the earthquake. From these aspects, we can see that it is very important to study the influence of earthquake on the mountain frame structure. In this paper, the influence of the number of spans on the seismic performance of the frame structure is analyzed from four aspects: the peak value of the inter story displacement, the peak value of the displacement between layers, the amplification coefficient of acceleration and the shear layer. the ancient people love building pillow Hill building, along the waterfront, the mountain building not only carry forward Chinese traditional landscape culture, but also make full use of the natural environment of mountains. 2/3 of the land area of ​​China is mountainous, especially in Sicilian, Yunnan, Chongqing, Guangzhou and other southwest of many buildings built in the mountains. Therefore, the mountain building is the only way to realize the sustainable development of the city. The earthquake in the life brought great damage, so far we still have not found a precise method to predict earthquakes, but to take some measures to reduce the harm to the people of the earthquake. from these aspects, we can see that it is very important to study the influence of earthquake on the mountain frame structure. In this paper, the influence of the number of spans on the seismic performance of the frame structure is analyzed from four aspects: the peak value of the inter story displacement, the pe ak value of the displacement between layers, the amplification coefficient of acceleration and the shear layer.