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目的 :分析 <40岁妇女子宫颈癌在临床及病理方面的特点。方法 :以 <40岁早期子宫颈癌 89例为研究组 ,选择同期手术 ,>40岁早期子宫颈癌 89例作为对照组 ,用SPSS分析软件对两组临床及病理学资料进行对照分析。结果 :<40岁患者中 ,发现不规则阴道流血或白带增多在 1个月内就诊者 85 .4% ,多于对照组 5 2 .9% (P <0 .0 0 5 ) ;其临床Ⅰa期患者高于对照组 (P <0 .0 5 ) ,肿瘤最大直径≥ 4cm者占 5 5 .1% ,高于对照组 39.3% (P <0 .0 5 ) ;病理类型腺癌占 18.0 % ,高于鳞癌 4.5 % (P<0 .0 0 5 )。肿瘤呈菜花型占 6 2 .9% ,高于对照组的 42 .7% (P <0 .0 0 5 ) ;两组的组织学分级及盆腔淋巴结转移率相似。 <40岁者预后差 ,其 5年生存率为 78.7%。结论 :<40岁的早期子宫颈癌预后差 ,对有不良预后因素者治疗应选用手术与放射联合治疗 ,必要时辅以化疗。
Objective: To analyze the clinical and pathological characteristics of cervical cancer in women <40 years old. Methods: 89 cases of early stage cervical cancer aged <40 years old were selected as the study group. 89 cases of early stage cervical cancer aged> 40 years as the control group were selected as the control group. The clinical and pathological data were analyzed by SPSS software. Results: In 40-year-old patients, irregular vaginal bleeding or leucorrhea increased 85.4% in 1 month, more than 52.9% in control group (P <0.05) (P <0.05). The maximum diameter of tumors ≥ 4 cm accounted for 51.5%, which was higher than that of the control group (39.3%, P <0.05). The pathological type of adenocarcinoma accounted for 18.0% , Higher than squamous cell carcinoma 4.5% (P <0.05). The tumor was cauliflower accounted for 62.9%, higher than the control group 42.7% (P <0.05); histological grade and pelvic lymph node metastasis rate were similar in both groups. <40 years of poor prognosis, the 5-year survival rate was 78.7%. Conclusion: The prognosis of early stage cervical cancer <40 years old is poor. For patients with adverse prognostic factors, the combination of surgery and radiotherapy should be used. Chemotherapy should be used if necessary.