本文报道了14例婴儿晚发性维生素K(Vit K)缺乏症。患儿以母乳喂养,出生2周～3月为多,临床特点为突然自发性出血、贫血和颅高压症。其中6例头颅CT证实颅内出血,3例实验室检查证实亚临床型胆汁淤积症(2例发病年龄稍大),提示原发性疾病在Vit K缺乏症中的意义,尤其是发病年龄稍大的患儿。文章还简述了当前国外预防Vit K缺乏症的有关论点,指出了口服vit K预防的必要性与可行性。 This article reports on 14 infants with late onset vitamin K (Vit K) deficiency. Children with breastfeeding, born two weeks to March as much, the clinical features of sudden spontaneous bleeding, anemia and intracranial hypertension. Six of them had intracerebral hemorrhage confirmed by head CT and three had laboratory tests confirming subclinical cholestasis (two patients had a slightly older age) suggesting the significance of primary disease in Vit K deficiency, especially in older patients Children. The article also briefly described the current foreign prevention of vitamin K deficiency related arguments, pointed out the need for oral vit K prevention and feasibility.