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目的观察甘精胰岛素联合阿卡波糖治疗老年2型糖尿病的有效性及安全性。方法选择60例应用口服降糖药血糖控制不佳的老年2型糖尿病患者,停用原有口服降糖药,给予甘精胰岛素联合阿卡波糖治疗,比较治疗前后空腹血糖、餐后血糖、糖化血红蛋白、低血糖发生情况。结果 60例患者治疗12周后,空腹血糖、餐后血糖、糖化血红蛋白下降与治疗前比较差异有统计学意义,低血糖发生率低。结论老年糖尿病患者口服降糖药治疗不能使血糖控制达标的可采用甘精胰岛素联合阿卡波糖治疗,能有效的控制空腹血糖及餐后血糖,且低血糖发生率低,是安全有效的治疗方法,值得推广的治疗方案。
Objective To observe the efficacy and safety of insulin glargine and acarbose in the treatment of type 2 diabetes in the elderly. Methods Sixty elderly patients with type 2 diabetes mellitus who were poorly controlled by oral hypoglycemic agents were enrolled in this study. The patients were treated with insulin glargine and acarbose. The fasting blood glucose, Glycated hemoglobin, hypoglycemia occurred. Results After 60 weeks of treatment, the fasting blood glucose, postprandial blood glucose and HbA1c decreased significantly compared with those before treatment, and the incidence of hypoglycemia was low. Conclusion The treatment of elderly diabetic patients with oral hypoglycemic agents can not make blood glucose control standard can be combined glargine and acarbose treatment, can effectively control fasting blood glucose and postprandial blood glucose, and low incidence of hypoglycemia, is a safe and effective treatment Method, worthy of promotion of treatment options.