［ 目的］ 制备聚维酮碘栓剂．［ 方法］ 以不同配比的甘油明胶基质，用热溶法制成甘油明胶聚维酮碘栓剂，通过质量检查和稳定性实验与半合成脂肪酸栓剂进行比较．［ 结果］ 一定配比甘油明胶聚维酮碘栓剂溶点高、硬度好，并释药度和水溶性好于半合成脂肪酸栓剂，可适应于高温地区贮存．［ 结论］聚维酮碘栓剂各项指标均符合药典规定 [Objective] To prepare povidone-iodine suppository. [Method] Glycerol gelatin povidone-iodine suppository was made by hot-dissolving method with glycerol gelatin matrix with different proportion, and compared with semi-synthetic fatty acid suppository by quality inspection and stability experiment. [Result] A certain proportion of glycerol gelatin povidone-iodine suppository had high melting point, good hardness, better release degree and water solubility than semisynthetic fatty acid suppository, which could be adapted to high temperature storage. [Conclusion] The povidone-iodine suppository indicators are in line with the provisions of Pharmacopoeia