口腔黏膜病是威胁人类健康及生活质量的疾病。大多数口腔黏膜病病因不明,这为临床及研究工作带来困难。为探索口腔黏膜病的发病机制及防治措施,黏膜病动物模型的建立显得尤为重要。国内外对于一些具体黏膜病,如口腔溃疡、口腔白斑、口腔癌等的模型建立有着详细介绍,但对口腔黏膜病的动物模型的总结性文章文献较少见,因此本文对口腔黏膜疾病较为成熟的动物模型做一阐述。 Oral mucosal disease is a disease that threatens human health and quality of life. The etiology of most oral mucosal diseases is unknown, which poses difficulties in clinical and research work. In order to explore the pathogenesis and prevention and treatment of oral mucosal diseases, the establishment of animal models of mucosal disease is particularly important. Domestic and foreign for some specific mucosal diseases, such as oral ulcers, oral leukoplakia, oral cancer and other models to establish a detailed introduction, but the animal models of oral mucosal disease summarize articles are rare, so this article is more mature oral mucosal disease Animal model to make an elaboration.