论文部分内容阅读
目的观察自拟养心安神汤联合右佐匹克隆片治疗失眠症的临床疗效。方法将200例失眠症患者随机分为治疗组和对照组,各100例,对照组采用右佐匹克隆片治疗,治疗组采用自拟养心安神汤联合右佐匹克隆片治疗,2周为1个疗程,1个疗程后观察2组患者治疗前后中医症状积分、匹兹堡睡眠质量指数(PQSI)和临床疗效等指标。结果治疗前2组患者的入睡困难、多梦易醒及神疲食少症状积分经统计学比较差异无统计学意义(P>0.05);治疗后2组患者的入睡困难、多梦易醒及神疲食少积分均低于治疗前,且治疗组低于对照组,差异均有统计学意义(P<0.05)。治疗前2组患者的PSQI评分比较差异无统计学意义(P>0.05),治疗后2组患者的PSQI评分均低于治疗前,且治疗组PSQI评分低于对照组,差异有统计学意义(P<0.05)。治疗后治疗组的临床总有效率为81.00%高于对照组的65.00%,差异有统计学意义(P<0.05)。治疗后治疗组出现丙氨酸氨基转移酶轻度升高2例,皮疹1例,对照组出现头痛2例,经对症治疗后好转,在血常规,肾功能及心电图等辅助检查未见明显异常。结论自拟养心安神汤联合右佐匹克隆片是治疗失眠症的一种有效方法,具有临床实际使用价值。
Objective To observe the clinical efficacy of self-made Yang Xin Anshen decoction combined with the treatment of insipidus. Methods 200 cases of insomnia were randomly divided into treatment group and control group, with 100 cases in each group. The control group was treated with dezopiclone tablets. The patients in treatment group were treated with Yangxinshenzhu Decoction combined with dexrazoxane tablets for 2 weeks One course of treatment and one course of treatment were observed before and after treatment of Chinese medicine symptom scores, Pittsburgh sleep quality index (PQSI) and clinical efficacy and other indicators. Results There was no significant difference between the two groups before treatment for difficulty falling asleep, more dreams and easy to wake up, and less symptom of mental fatigue (P> 0.05). After treatment, the two groups of patients had difficulty falling asleep, The results showed that there was a significant difference between the two groups (P <0.05). There was no significant difference in PSQI scores between the two groups before treatment (P> 0.05). PSQI scores of two groups were lower than before treatment, PSQI score of the treatment group was lower than that of the control group (P> 0.05), the difference was statistically significant P <0.05). The total effective rate of the treatment group after treatment was 81.00%, which was significantly higher than that of the control group (65.00%) (P <0.05). In the treatment group, there were 2 mild cases of alanine aminotransferase, 1 case of skin rash and 2 cases of headache in the control group. After symptomatic treatment, there was no obvious abnormality in auxiliary examination such as blood routine, renal function and electrocardiogram . CONCLUSION: Self-made Yangxin Anshen Decoction combined with dexrazepam is an effective method to treat insomnia and has clinical practical value.