代谢组学是继基因组学、转录组学、蛋白质组学之后系统生物学中形成的另一重要组成部分,也是目前组学领域研究的热点之一。代谢组学技术对理解细胞功能来讲是一种十分重要的功能基因组学技术,因为代谢组直接反应了细胞的生理状态,利用代谢组学技术很有可能去发现细胞新的生化途径并解释其正常的或病理的功能。该文就代谢组学所涉及的技术及其在微生物领域的应用进行综述。 Metabolomics is another important part of system biology after genomics, transcriptomics and proteomics. It is also one of the hot spots in the field of histology. Metabolomics is a very important functional genomics technique for understanding cellular functions because metabolomes directly reflect the physiological state of the cells and it is quite possible to use metabonomics techniques to find new biochemical pathways of cells and to explain their Normal or pathological function. This article reviews the technologies involved in metabonomics and their applications in the field of micro-organisms.