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目的:分析咳嗽变异性哮喘的特点,探讨采用阿斯美胶囊联合富马酸酮替芬片治疗咳嗽变异性哮喘的临床效果,为临床提供参考。方法:选取84例咳嗽变异性哮喘患者,随机分为对照组和治疗组,对照组采用富马酸酮替芬片和布地奈德气雾剂进行治疗,治疗组采用富马酸酮替芬片和阿斯美胶囊联合治疗,观察两组患者的临床效果、肺功能及不良反应等。结果:对照组总有效率为71.4%,治疗组为95.2%,治疗组总有效率较对照组有显著性差异(χ2=4.286,P<0.05);治疗组肺功能指标改善程度明显高于对照组,具有显著性差异(P<0.05);两组均未发生严重的不良反应。结论:阿斯美胶囊联合富马酸酮替芬片用于治疗咳嗽变异性哮喘,可显著改善患者的肺功能,提高临床治疗的效果,且安全有效,具有一定的临床借鉴意义。
OBJECTIVE: To analyze the characteristics of cough variant asthma and to explore the clinical effect of Aspirin Capsules combined with ketotifen fumarate tablets in the treatment of cough variant asthma, so as to provide a reference for clinical practice. Methods: Eighty-four patients with cough variant asthma were randomly divided into control group and treatment group. The control group was treated with ketotifen fumarate tablets and budesonide aerosol. The treatment group was treated with ketotifen fumarate tablets And Asimi Capsules combined treatment, observation of two groups of patients with clinical effects, lung function and adverse reactions. Results: The total effective rate was 71.4% in the control group and 95.2% in the treatment group. The total effective rate in the treatment group was significantly different from that in the control group (χ2 = 4.286, P <0.05). The improvement of pulmonary function in the treatment group was significantly higher than that in the control group Group, with significant difference (P <0.05); no serious adverse reactions occurred in both groups. Conclusion: Asme capsule combined with ketotifen fumarate tablets for the treatment of cough variant asthma can significantly improve patients’ lung function, improve the effect of clinical treatment, and is safe and effective, and has certain clinical significance.