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[目的]评价上海市不同区域结直肠癌患者生命质量的差异,为采取地域性的防治措施提供参考依据。[方法]2013年4~7月在上海进行横断面调查研究,共回收有效问卷1398份,调查内容包括社会人口学、肿瘤诊疗、行为生活方式等,以及EORTC QLQ-C30和FACT-G量表中文版评测。[结果]根据聚类分析将上海区县分为两类:Ⅰ类以中心城区为主;Ⅱ类以郊区或郊县为主。调整社会人口学和肿瘤诊断治疗情况等因素,Ⅰ类区域的结直肠癌患者的EORTC QLQ-C30和FACT-G量表评分得分均显著性低于Ⅱ类区域患者(Padjusted<0.05)。[结论]上海中心城区的结直肠癌患者总体生命质量可能低于郊区或郊县的患者,应给予中心城区的结直肠癌患者更多的关注。
[Objective] To evaluate the difference of quality of life among patients with colorectal cancer in different regions of Shanghai, and provide reference for taking regional prevention and treatment measures. [Methods] A cross-sectional investigation was conducted in Shanghai from April to July 2013. A total of 1398 valid questionnaires were collected. The survey included social demography, oncology diagnosis and treatment, behavioral lifestyle, and EORTC QLQ-C30 and FACT-G scales Chinese version evaluation. [Result] According to the cluster analysis, the districts and counties in Shanghai were divided into two categories: the first type was centered in downtown area; the second type was suburban or suburban. Adjusting for socio-demography and diagnosis and treatment of cancer, the scores of EORTC QLQ-C30 and FACT-G in patients with type I colorectal cancer were significantly lower than those in patients with type II (Padjusted <0.05). [Conclusion] The overall quality of life of patients with colorectal cancer in downtown Shanghai may be lower than that in suburban or suburban areas, and more attention should be paid to patients with colorectal cancer in downtown area.