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目的研究分析2型糖尿病患者合并非糖尿病性肾脏疾病(NDRD)的临床病理特点,旨在提高该病的早期诊断率。方法报道经治疗的1例2型糖尿病合并NDRD(血管炎)的临床资料,并分析文献报道的91例患者的资料。结果2型糖尿病可以合并多种非糖尿病性肾损害,包括各种原发性或继发性肾脏疾病,其中以IgA肾病为最多。无糖尿病视网膜病变、血尿、血糖控制满意、急性肾衰竭高度提示NDRD的存在。结论2型糖尿病合并肾损害不一定是糖尿病肾病,可以是NDRD,早期诊断和有效治疗有助于改善预后。
Objective To study the clinicopathological features of type 2 diabetic patients with non-diabetic renal disease (NDRD) and to improve the early diagnosis rate of this disease. Methods The clinical data of 1 type 2 diabetes mellitus complicated with NDRD (vasculitis) treated were reported and the data of 91 patients reported in the literature were analyzed. Results Type 2 diabetes can be combined with a variety of non-diabetic kidney damage, including a variety of primary or secondary kidney disease, of which IgA nephropathy is the most. No diabetic retinopathy, hematuria, blood glucose control satisfaction, acute renal failure is highly suggestive of the presence of NDRD. Conclusions Type 2 diabetes with renal impairment is not necessarily diabetic nephropathy and may be NDRD. Early diagnosis and effective treatment may improve prognosis.