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很多作者曾研究过阿米巴肝脓肿(ALA)患者的细胞免疫功能,尽管各家研究的结果有些不一致,但至少说明ALA患者有细胞介导免疫功能方面的变化。本文作者研究了急性ALA患者的细胞免疫,检测方法用体外淋巴细胞转化试验——分别以特异性的溶组织内阿米巴抗原和非特异性的植物血凝素(PHA)作淋巴细胞有丝分裂刺激原,和T、B淋巴细胞绝对计数。研究对象为26名ALA患者,其中23名为男性,年龄1～54岁,平均为31.5岁,不伴有细菌性肝脓肿,抗阿米巴治疗有效,其中13名患者脓液直接镜检或培养证明有溶组织内阿米巴。全部病人都有年龄、性别、种族相仿的配对对照组。研究组血清阿米巴乳胶扩散试验均呈强阳性,对照组则阴性。
Many authors have studied the cellular immune function in patients with amoebic liver abscess (ALA). Although the results of each study are somewhat inconsistent, at least shows that ALA patients have cell-mediated immune function changes. The authors studied cellular immunity in patients with acute ALA. The assay was performed in vitro using lymphocyte transformation assays - using specific Entamoeba histolytica and non-specific phytohaemagglutinin (PHA) as lymphocyte mitogen-activated , And T, B lymphocytes absolute count. The study population was 26 ALA patients, 23 of whom were male, aged from 1 to 54 years (mean, 31.5 years) with no bacterial liver abscess and anti-amoebic treatment. Thirteen patients underwent direct microscopy or pus Cultivation of Entamoeba histolytica. All patients had matched age, gender and ethnicity matched control group. Study group serum amoeba latex diffusion test showed a strong positive, while the control group was negative.