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目的:探讨弥散加权成像(diffusion weighted imaging,DWI)序列和液体衰减反转恢复技术(fluid attenuated inversion recovery,FLAIR)在不同时期脑梗死诊断中的应用价值。方法:选取120例不同时期的脑梗死患者作为研究对象,分别行1.5T磁共振DWI和FLAIR序列检查,以双盲法对比分析发现病例的敏感度和病灶面积。结果::DWI、FLAIR发现病例的敏感度:在超急性期内,分别为100%和26.67%(P<0.05);在急性期内,均为100%;在亚急性期内,分别为80%和86.67%(P>0.05);在慢性期内,分别为11.11%和94.44%(P<0.05)。梗塞灶面积显示,在72 h内DWI大于FLAIR(P<0.05),亚急性期间基本相当(P>0.05),慢性期FLAIR大于DWI(P<0.05)。结论:联合应用DWI和FLAIR能准确诊断不同时期脑梗死,并有助对脑梗死进行分期和新旧病灶的鉴别。
Objective: To investigate the value of diffusion weighted imaging (DWI) and fluid attenuated inversion recovery (FLAIR) in the diagnosis of cerebral infarction at different stages. Methods: One hundred and twenty patients with different stages of cerebral infarction were enrolled in this study. 1.5T magnetic resonance imaging (DWI) and FLAIR were performed respectively. The sensitivity and lesion area of the cases were analyzed by double-blind method. RESULTS: The sensitivity of the cases detected by DWI and FLAIR were 100% and 26.67% (P <0.05) in the hyperacute phase and 100% in the acute phase. In the subacute phase, they were 80 % And 86.67% respectively (P> 0.05). In the chronic phase, they were 11.11% and 94.44% respectively (P <0.05). Infarct size showed that DWI was greater than FLAIR in 72 h (P <0.05), subacute period was basically the same (P> 0.05), and FLAIR in chronic phase was higher than DWI (P <0.05). Conclusion: The combined application of DWI and FLAIR can accurately diagnose cerebral infarction at different stages and help identify the stage of the cerebral infarction and the new and old lesions.