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目的探讨食物源性C组β型溶血性链球菌感染的临床特点、治疗方法及转归。方法回顾分析河北医科大学第一医院2003-05-28—2003-06-03确诊的51例C组β型溶血性链球菌感染的临床特点。结果51例患者均为食源性感染,临床表现主要为咽充血51例(100%)、发热44例(86%)、扁桃体肿大39例(76.5%)、头痛31例(60.8%)、全身酸痛23例(45.1%)。消化道症状不明显。咽拭子采样17份,细菌培养均阳性;漱口液采样44份,细菌培养阳性23份(52.3%)。培养细菌均为C组β型溶血停乳链球菌类马亚种。51例患者经抗感染治疗均痊愈出院,无并发症。结论与食物污染有关的集体发病患者表现为发热、头痛、全身酸痛、咽痛、咽部充血及扁桃体肿大应考虑到C组链球菌感染的可能,污染食物、咽拭子、漱口液培养可以明确诊断,如未合并严重基础疾病并给予及时有效的抗感染治疗多预后良好。
Objective To investigate the clinical characteristics, treatment and prognosis of β-type hemolytic streptococcal infection in food-derived group C Methods Retrospective analysis of the First Hospital of Hebei Medical University 2003-05-28-2003-06-03 confirmed 51 cases of C group β-hemolytic streptococcal clinical features. Results All the 51 patients were foodborne. The main clinical manifestations were pharyngeal congestion in 51 cases (100%), fever in 44 cases (86%), tonsil enlargement in 39 cases (76.5%), headache in 31 cases (60.8% 23 cases of body aches (45.1%). Gastrointestinal symptoms are not obvious. 17 pharyngeal swabs were collected for bacterial culture, 44 samples were collected for mouthwash and 23 (52.3%) were positive for bacterial culture. The cultured bacteria are all Group C beta-type hemolysis Streptococcus dysp. 51 patients were cured by anti-infection were discharged, no complications. Conclusions Patients with group disease associated with food contamination may have fever, headache, body aches, sore throat, pharyngeal hyperemia and tonsil enlargement. C group Streptococcus infection may be considered. Contaminated food, throat swab, and mouthwash Can be a clear diagnosis, if not combined with serious underlying diseases and give timely and effective anti-infective treatment with good prognosis.