神经干细胞 (NSC)多分化潜能的研究使人们对神经系统发生及中枢神经系统的损伤修复有了深入了解。NSC在体内的分化过程受各种信号分子的作用。干细胞在体内所受到的各类细胞因子的影响 ,最终将在基因水平的调控环节发挥作用。NSC的移植模型证明移植后干细胞保持着多分化潜能 ,且局部微环境信号在诱导分化方面起着重要作用 Research on the potential of neural stem cells (NSCs) to differentiate has gained insight into the development of the nervous system and the repair of damage to the central nervous system. The differentiation of NSC in vivo is affected by various signaling molecules. Stem cells in the body by the various types of cytokines, will eventually play a role in the regulation of genetic level. Transplantation models of NSCs demonstrate that stem cells after transplantation retain pluripotency and that local microenvironment signals play an important role in inducing differentiation