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目的了解临床标本分离的粘质沙雷菌感染分布特征及其耐药情况,以便指导临床抗菌药物的合理使用。方法通过回顾性调查方法,对某医院临床标本分离的粘质沙雷菌感染分布和药敏试验结果进行分析。结果该医院从患者送检标本中分离出粘质沙雷菌98株,其中71株分离自病人痰液标本,占分离菌株总数的72.45%;其次为尿液和分泌物,分别占13.27%和6.12%。粘质沙雷菌感染患者主要分布在重症监护病房(ICU),构成比为38.78%;其次为呼吸内科和脑外科,构成比分别占12.24%和10.20%。临床分离的粘质沙雷菌对多数常用抗菌药物比较敏感,对哌拉西林的耐药率为52.04%,发现2株粘质沙雷菌对碳青霉烯类抗菌药物耐药。结论该医院临床分离的粘质沙雷菌主要来自呼吸道感染患者痰液,ICU是该菌感染的主要科室,该菌对常用抗菌药物较敏感。
Objective To understand the distribution characteristics of drug-resistant Serratia marcescens isolated from clinical specimens and its drug resistance in order to guide the rational use of clinical anti-bacterial drugs. Methods The retrospective investigation method was used to analyze the distribution and susceptibility test results of Serratia marcescens isolated from clinical specimens of a hospital. Results The hospital isolated 98 strains of Serratia marcescens from the patient samples, of which 71 were isolated from the sputum of patients, accounting for 72.45% of the total isolates; followed by urine and secretions, accounting for 13.27% and 6.12%. Patients with Serratia marcescens infection were mainly distributed in intensive care unit (ICU), with a constituent ratio of 38.78%, followed by respiratory medicine and brain surgery, with a proportion of 12.24% and 10.20% respectively. Clinical isolates of Serratia marcescens sensitive to most commonly used antibiotics, resistance to piperacillin was 52.04%, found two strains of Serratia marcescens carbapenem antibiotic resistance. Conclusion The clinically isolated Serratia marcescens mainly comes from the sputum of patients with respiratory tract infection. The ICU is the main infection of the bacteria. The bacteria are sensitive to common antibiotics.